Assessment of accuracy of incisional and needle biopsy in soft-tissue tumors in a brazilian center of reference

Abstract

Objective: To assess the accuracy of incisional biopsies (IB) and needle biopsies (NB) in soft-tissue tumors treated at a Brazilian center of reference, as well as the variables related to the demographic profile and treatment established. Methods: A retrospective, descriptive and observational study was conducted with patients with malignant soft tissue tumoral lesions, of indeterminate and intermediary malignancy, subjected to IB or NB at the institution from January 2010 to December 2019. Results: 114 biopsies were performed in soft-tissue tumors of malignant lesions, of indeterminate and intermediary malignancy; of these 90 biopsies, 61 (67.7%) were IB and 29 (25.4%) were NB. It was necessary to perform a new collection in 5 cases among the NB (17.2%) and 1 case among the IB (1.6%). The IB accuracy was 83.6, while NB was 62.1. Of the 18 patients subjected to surgical treatment with radical margin, 7 were initially subjected to NB (36.8%) and 9 to IB (17.3%). Conclusion: Despite the advantages inherent to the percutaneous procedure of NB, IB must still be considered a diagnostic option in soft tissue tumors with high heterogeneity and degree of necrosis. Level of Evidence III; Diagnostic Studies - Investigating a Diagnostic Test.

Objetivo: Avaliar a acurácia das biópsias incisionais (BI) e biópsias por agulha (BA) nos tumores de partes moles atendidos num centro de referência brasileiro, bem como as variáveis relacionadas ao perfil demográfico e tratamento instituído. Métodos: Foi realizado um estudo retrospectivo, descritivo e observacional, com pacientes com lesões tumorais de partes moles malignas, de malignidade indeterminada e intermediárias, submetidos a BI ou BA na instituição no período de janeiro de 2010 a dezembro de 2019. Resultados: Foram realizadas 114 biópsias de tumores de partes moles de lesões malignas, de malignidade indeterminada e intermediárias, destas 90 biópsias, 61 (67,8%) foram BI e 29 (25,4%) BA. Foi necessário nova coleta em 5 casos dentre as BA (17,2%) e 1 caso das BI (1,6%). A acurácia da BI foi de 83,6, enquanto da BA foi de 62,1. Dos 18 pacientes submetidos a tratamento cirúrgico com margem radical, 7 foram inicialmente submetidos à BA (36,8%) e 9 à BI (17,3%). Conclusão: Apesar das vantagens inerentes ao procedimento percutâneo da BA, a BI deve ainda ser considerada como opção diagnóstica em tumores de partes moles com alta heterogeneidade e grau de necrose. Nível de Evidência III; Estudo diagnóstico – Investigação de um exame para diagnóstico.